Gastroenterology Unit, John Hunter Hospital and University of Western Sydney, Sydney and Cathay Herbal Labs, Sydney, Australia.

The treatment of chronic hepatitis C is relatively unsatisfactory and many patients have turned to unproven alternative medications to modify the course of their illness. We report a study of a Chinese herbal medicine preparation CH100 in the management of chronic hepatitis C.

Patients with documented chronic hepatitis C were randomly allocated to receive active herbal or placebo tablets (5 tablets thrice daily) for 6 months. Patients were followed monthly and evaluated by a western and a traditional Chinese medical practitioner . Therapy was monitored by measurement of liver function tests, creatinine and full blood count on a monthly basis.

20 patients in each group were well matched for age, sex, duration of
illness, previous interferon therapy and alcohol intake. Active Chinese
herbal medication was associated with a significant reduction in ALT levels over the 6 month study period (p<0.03). No patient cleared the virus but 4 normalised their ALT on active treatment.

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